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The vials are made using an old glass technique called lampworking, which dates back to the 16th century. All glass vials are handcrafted right down to the stopper , each one is unique from the other. Duplication of one vial to another is impossible . Size and shapes are possible. The vials are made from borosilicate glass, which is used in cookware, neon sign making and chemistry labs, because of its strong resistance to thermal cracking and its chemical structure of hardness.